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McDonald's Quarter Pounder® with Cheese Deluxe is a fresh take on a Quarter Pounder® classic burger. Crisp shredded lettuce and three Roma tomato slices top a ¼ lb.* of 100% McDonald’s fresh beef that’s hot, deliciously juicy and cooked when you order. Seasoned with just a pinch of salt and pepper and sizzled on our flat iron grill. Layered with two slices of melty American cheese, creamy mayo, slivered onions and tangy pickles on a soft, fluffy sesame seed hamburger bun. There are 630 calories in a Quarter Pounder with Cheese Deluxe. Grab your QPC Deluxe through the drive thru or with McDonald's curbside pickup when you Mobile Order & Pay! McDonald's App download and registration required.